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Rockland
GLS2 Polyclonal Antibody
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FIGURE: 1 / 3
GLS2 Antibody (600-401-BL8) in ICC/IF
Immunofluorescence Microscopy of Rabbit anti-GLS2 antibody. Tissue: Human Kidney cells. Primary antibody: GLS2 antibody at 20 µg/mL. Secondary antibody: Fluorescein rabbit secondary antibody at 1:20,000. Localization: GLS2 is located in the mitochondrion. Staining: GLS2 as red fluorescent signal.
Product Details
600-401-BL8
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-GLS2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 18 amino acid synthetic peptide near the internal region terminus of human GLS2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: breast cell glutaminase; GLS; glutaminase 2 (liver, mitochondrial); glutaminase GA; glutaminase I; Glutaminase liver isoform, mitochondrial; L hL L-glutaminase; L hLGA; L-glutaminase; L-glutamine amidohydrolase; LGA; liver mitochondrial glutaminase; phosphate-activated glutaminase; phosphate-dependent glutaminase
Gene Aliases: A330074B06Rik; AI195532; GA; GLS; GLS2; hLGA; Kiaa4146; LGA
UniProt ID: (Human) Q9UI32, (Rat) P28492, (Mouse) Q571F8
Entrez Gene ID: (Human) 27165, (Rat) 192268, (Mouse) 216456
cellular amino acid metabolic process
glutamate biosynthetic process
glutamine catabolic process
cellular amino acid biosynthetic process
glutamate secretion
regulation of apoptotic process
reactive oxygen species metabolic process
positive regulation of protein targeting to mitochondrion
glutamine metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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