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Invitrogen
GLS2 Polyclonal Antibody
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FIGURE: 1 / 6
GLS2 Antibody (PA5-78475) in WB
Western Blot using GLS2 Polyclonal Antibody (Product # PA5-78475). Various whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with GLS2 Polyclonal Antibody (Product # PA5-78475) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-78475
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Mouse GLS2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Huh-7, HepG2, mouse liver, rat liver
Predicted Reactivity: Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: breast cell glutaminase; GLS; glutaminase 2 (liver, mitochondrial); glutaminase GA; glutaminase I; Glutaminase liver isoform, mitochondrial; L hL L-glutaminase; L hLGA; L-glutaminase; L-glutamine amidohydrolase; LGA; liver mitochondrial glutaminase; phosphate-activated glutaminase; phosphate-dependent glutaminase
Gene Aliases: A330074B06Rik; AI195532; GA; GLS; GLS2; hLGA; Kiaa4146; LGA
UniProt ID: (Human) Q9UI32, (Rat) P28492, (Mouse) Q571F8
Entrez Gene ID: (Human) 27165, (Rat) 192268, (Mouse) 216456
cellular amino acid metabolic process
glutamate biosynthetic process
glutamine catabolic process
cellular amino acid biosynthetic process
glutamate secretion
regulation of apoptotic process
reactive oxygen species metabolic process
positive regulation of protein targeting to mitochondrion
glutamine metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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