Search
Abnova
GLUL Polyclonal Antibody, MaxPab™
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 2
GLUL Antibody (H00002752-D01P) in WB
Western Blot analysis of GLUL expression in transfected 293T cell line (H00002752-T01) by GLUL MaxPab polyclonal antibody.
Lane 1: GLUL transfected lysate(42.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: GLUL transfected lysate(42.10 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00002752-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GLUL (NP_002056.2, 1 a.a. approximately 373 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MTTSASSHLN KGIKQVYMSL PQGEKVQAMY IWIDGTGEGL RCKTRTLDSE PKCVEELPEW NFDGSSTLQS EGSNSDMYLV PAAMFRDPFR KDPNKLVLCE VFKYNRRPAE TNLRHTCKRI MDMVSNQHPW FGMEQEYTLM GTDGHPFGWP SNGFPGPQGP YYCGVGADRA YGRDIVEAHY RACLYAGVKI AGTNAEVMPA QWEFQIGPCE GISMGDHLWV ARFILHRVCE DFGVIATFDP KPIPGNWNGA GCHTNFSTKA MREENGLKYI EEAIEKLSKR HQYHIRAYDP KGGLDNARRL TGFHETSNIN DFSAGVANRS ASIRIPRTVG QEKKGYFEDR RPSANCDPFS VTEALIRTCL LNETGDEPFQ YKN
Target Information
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: cell proliferation-inducing protein 59; GLNA; Glutamate ammonia ligase; glutamate decarboxylase; Glutamate--ammonia ligase; glutamate-ammonia ligase (glutamine synthase); glutamine synthase; Glutamine synthetase; glutamine synthetase I; GS; Palmitoyltransferase GLUL; Proliferation inducing protein 43; proliferation-inducing protein 43; unnamed protein product
Gene Aliases: DEE116; GLNS; GLUL; GS; PIG43; PIG59
UniProt ID: (Human) P15104, (Mouse) P15105
Entrez Gene ID: (Human) 2752, (Mouse) 14645
nucleotide binding
catalytic activity
glutamate-ammonia ligase activity
protein binding
ATP binding
transferase activity
ligase activity
protein-cysteine S-palmitoyltransferase activity
identical protein binding
metal ion binding
magnesium ion binding
glutamate decarboxylase activity
glutamate binding
lyase activity
manganese ion binding
dynein light chain binding
ligase
angiogenesis
glutamate catabolic process
glutamine biosynthetic process
cell proliferation
cellular response to starvation
response to glucose
regulation of endothelial cell migration
protein palmitoylation
ribosome biogenesis
positive regulation of erythrocyte differentiation
cellular ammonia homeostasis
regulation of sprouting angiogenesis
regulation of protein localization to nucleolus
glutamate metabolic process
nitrogen compound metabolic process
ammonia assimilation cycle
positive regulation of insulin secretion
positive regulation of epithelial cell proliferation
protein homooligomerization
positive regulation of synaptic transmission, glutamatergic
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support