Product References
KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition.
iScience
Koppula P,Olszewski K,Zhang Y,Kondiparthi L,Liu X,Lei G,Das M,Fang B,Poyurovsky MV,Gan B
PA5-16793 was used in Western Blot to show that KEAP1 deficiency promotes glucose dependency in lung cancer cells, and KEAP1-mutant/deficient lung cancer cells are more vulnerable to glucose deprivation than their WT counterparts.
Fri Jun 25 00:00:00 EDT 2021
Placental Glucose Transporters and Response to Bisphenol A in Pregnancies from of Normal and Overweight Mothers.
International journal of molecular sciences
Ermini L,Nuzzo AM,Ietta F,Romagnoli R,Moretti L,Masturzo B,Paulesu L,Rolfo A
Published figure using GLUT1 polyclonal antibody (Product # PA5-16793) in Western Blot
Mon Jun 21 00:00:00 EDT 2021
NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma.
JCI insight
Hu W,Liu Z,Salato V,North PE,Bischoff J,Kumar SN,Fang Z,Rajan S,Hussain MM,Miao QR
PA5-16793 was used in Immunohistochemistry to suggest that NGBR served as a RAS modulator in controlling the growth and differentiation of HemSCs.
Mon Feb 08 00:00:00 EST 2021
Ibrutinib Resistance Is Reduced by an Inhibitor of Fatty Acid Oxidation in Primary CLL Lymphocytes.
Frontiers in oncology
Galicia-Vázquez G,Aloyz R
PA5-16793 was used in Western Blotting to define the metabolic traits associated with ibrutinib resistance.
Thu Oct 01 00:00:00 EDT 2020
Steroids Regulate SLC2A1 and SLC2A3 to Deliver Glucose Into Trophectoderm for Metabolism via Glycolysis.
Endocrinology
Kramer AC,Steinhauser CB,Gao H,Seo H,McLendon BA,Burghardt RC,Wu G,Bazer FW,Johnson GA
PA5-16793 was used in Immunohistochemistry to conclude that glucose can be transported into the uterine lumen by SLC2A1, and then into conceptuses by SLC2A3.
Sat Aug 01 00:00:00 EDT 2020
The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma.
Aging
Wang J,Wang Z,Yuan J,Wang J,Shen X
PA5-16793 was used in Immunohistochemistry to investigate whether and how O-GlcNAcylation and ACSL4 regulate each other and HCC progression.
Fri May 01 00:00:00 EDT 2020
The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma.
Aging
Wang J,Wang Z,Yuan J,Wang J,Shen X
PA5-16793 was used in Immunohistochemistry to investigate whether and how O-GlcNAcylation and ACSL4 regulate each other and HCC progression.
Fri May 01 00:00:00 EDT 2020
The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma.
Aging
Wang J,Wang Z,Yuan J,Wang J,Shen X
PA5-16793 was used in Immunohistochemistry to investigate whether and how O-GlcNAcylation and ACSL4 regulate each other and HCC progression.
Fri May 01 00:00:00 EDT 2020
The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma.
Aging
Wang J,Wang Z,Yuan J,Wang J,Shen X
PA5-16793 was used in Immunohistochemistry to investigate whether and how O-GlcNAcylation and ACSL4 regulate each other and HCC progression.
Fri May 01 00:00:00 EDT 2020
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer.
Nature cell biology
Liu X,Olszewski K,Zhang Y,Lim EW,Shi J,Zhang X,Zhang J,Lee H,Koppula P,Lei G,Zhuang L,You MJ,Fang B,Li W,Metallo CM,Poyurovsky MV,Gan B
PA5-16793 was used in Western Blotting to identify a coupling between SLC7A11-associated cystine metabolism and the pentose phosphate pathway, and uncover an accompanying metabolic vulnerability for therapeutic targeting in SLC7A11high cancers.
Wed Apr 01 00:00:00 EDT 2020
Natural polyphenols as sirtuin 6 modulators.
Scientific reports
Rahnasto-Rilla M,Tyni J,Huovinen M,Jarho E,Kulikowicz T,Ravichandran S,A Bohr V,Ferrucci L,Lahtela-Kakkonen M,Moaddel R
PA5-16793 was used in Western Blotting to show that flavonoids can alter SIRT6 activity in a structure dependent manner.
Wed Mar 07 00:00:00 EST 2018
Galectin-3 induced by hypoxia promotes cell migration in thyroid cancer cells.
Oncotarget
Zheng J,Lu W,Wang C,Xing Y,Chen X,Ai Z
Published figure using GLUT1 polyclonal antibody (Product # PA5-16793) in Immunofluorescence
Fri Nov 24 00:00:00 EST 2017
Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.
Nature communications
Cogger KF,Sinha A,Sarangi F,McGaugh EC,Saunders D,Dorrell C,Mejia-Guerrero S,Aghazadeh Y,Rourke JL,Screaton RA,Grompe M,Streeter PR,Powers AC,Brissova M,Kislinger T,Nostro MC
Published figure using GLUT1 polyclonal antibody (Product # PA5-16793) in Immunocytochemistry
Thu Aug 24 00:00:00 EDT 2017
Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models.
PloS one
Barbone D,Follo C,Echeverry N,Gerbaudo VH,Klabatsa A,Bueno R,Felley-Bosco E,Broaddus VC
PA5-16793 was used in immunohistochemistry - paraffin section to assess the activity of a novel dual PI3K/mTOR inhibitor on mesothelioma
Wed May 11 00:00:00 EDT 2016
Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia.
PloS one
Sun Y,George J,Rocha S
PA5-16793 was used in western blot to study the effect of allopurinol treatment during hypoxia
Thu Feb 04 00:00:00 EST 2016
Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy.
Oncotarget
Weijer R,Broekgaarden M,Krekorian M,Alles LK,van Wijk AC,Mackaaij C,Verheij J,van der Wal AC,van Gulik TM,Storm G,Heger M
PA5-16793 was used in immunohistochemistry to analyze inhibition of hypoxia inducible factor 1 and acriflavine in sensitizing perihilar cholagiocarcinomas to photodynamic therapy
Tue Jan 19 00:00:00 EST 2016
Monitoring hypoxia and vasculature during bevacizumab treatment in a murine colorectal cancer model.
Contrast media & molecular imaging
Heijmen L,Ter Voert EG,Punt CJ,Heerschap A,Oyen WJ,Bussink J,Sweep CG,Laverman P,Span PN,de Geus-Oei LF,Boerman OC,van Laarhoven HW
PA5-16793 was used in immunohistochemistry to use a murine model of colorectal cancer to study the effects of bevacizumab therapy on tumor hypoxia and vascular density
Mon Nov 09 00:00:00 EST 2015
Vesicular glutamate transporter 1 orchestrates recruitment of other synaptic vesicle cargo proteins during synaptic vesicle recycling.
The Journal of biological chemistry
Pan PY,Marrs J,Ryan TA
PA5-16793 was used in immunohistochemistry - frozen section to investigate factors that regulate the retrieval of synaptic vesicles
Fri Sep 11 00:00:00 EDT 2015
Multiparametric MRI as an early biomarker of individual therapy effects during concomitant treatment of brain tumours.
NMR in biomedicine
Lemasson B,Bouchet A,Maisin C,Christen T,Le Duc G,Rémy C,Barbier EL,Serduc R
PA5-16793 was used in immunohistochemistry - frozen section to use rats to assess the ability of multiparametric MRI to identify the early effects of individual treatment on brain tumors
Tue Sep 01 00:00:00 EDT 2015
Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling.
Developmental cell
Zhou Y,Nathans J
PA5-16793 was used in immunohistochemistry - paraffin section to evaluate the role of Gpr124 in CNS angiogenesis and blood-brain barrier integrity
Mon Oct 27 00:00:00 EDT 2014
Kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon: ultrastructural observation and immunohistochemistry staining reveal the trapping of blood components.
Ultrastructural pathology
Yuan SM,Hong ZJ,Chen HN,Shen WM,Zhou XJ
PA5-16793 was used in immunohistochemistry to report on a case of kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon in an infant
Sun Dec 01 00:00:00 EST 2013
Immunohistochemical expression of GLUT-1 and Ki-67 in chronic plaque psoriasis.
The American Journal of dermatopathology
Abdou AG,Maraee AH,Eltahmoudy M,El-Aziz RA
PA5-16793 was used in immunohistochemistry to study the expression and biological significance of Glut1 and Ki67 in chronic plaque psoriasis
Tue Oct 01 00:00:00 EDT 2013
18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1α, glucose transporter-1 and vascular endothelial growth factor in thymic epithelial tumours.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Toba H,Kondo K,Sadohara Y,Otsuka H,Morimoto M,Kajiura K,Nakagawa Y,Yoshida M,Kawakami Y,Takizawa H,Kenzaki K,Sakiyama S,Bando Y,Tangoku A
PA5-16793 was used in immunohistochemistry to study the the clinical value of the relationships between fluorodeoxyglucose-PET/CT and HIF-1alpha, Glut1 and VEGF in thymic epithelial tumors
Thu Aug 01 00:00:00 EDT 2013
Synchrotron microbeam radiation therapy induces hypoxia in intracerebral gliosarcoma but not in the normal brain.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Bouchet A,Lemasson B,Christen T,Potez M,Rome C,Coquery N,Le Clec'h C,Moisan A,Bräuer-Krisch E,Leduc G,Rémy C,Laissue JA,Barbier EL,Brun E,Serduc R
PA5-16793 was used in immunohistochemistry to study the differential effects of synchrotron microbeam radiation therapy on intracerebral gliosarcoma and normal brain tissue and the significance for tumor hypoxia
Mon Jul 01 00:00:00 EDT 2013
Fusion of [(18)F]FDG PET with fluorescence diffuse optical tomography to improve validation of probes and tumor imaging.
Molecular imaging and biology
Garofalakis A,Dubois A,Thézé B,Czarny B,Tavitian B,Ducongé F
PA5-16793 was used in immunohistochemistry to compare the distribution of 2-deoxy-2-[(18)F]fluoro-D-glucose ([(18)F]FDG) in tumors with three fluorescent probes
Sat Jun 01 00:00:00 EDT 2013
Congenital melanocytic nevus with features of hybrid schwannoma/perineurioma.
Journal of cutaneous pathology
Wang L,Wang G,Gao T
PA5-16793 was used in immunohistochemistry to report on a case of congenital melanocytic nevus
Wed May 01 00:00:00 EDT 2013
The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.
The Biochemical journal
Bett JS,Ibrahim AF,Garg AK,Kelly V,Pedrioli P,Rocha S,Hay RT
PA5-16793 was used in western blot to study the regulation of HIF1-alpha mRNA stability by P-body USP52/PAN2
Mon Apr 15 00:00:00 EDT 2013
Subfield-specific neurovascular remodeling in the entorhino-hippocampal-organotypic slice culture as a response to oxygen-glucose deprivation and excitotoxic cell death.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Chip S,Nitsch C,Wellmann S,Kapfhammer JP
PA5-16793 was used in western blot to study the effects of oxygen/glucose deprivation and excitotoxic neuronal death on neurovascular changes using an organotypic entorhino-hippocampal culture model
Mon Apr 01 00:00:00 EDT 2013
Transforming growth factor-β1 may be a key mediator of the fibrogenic properties of neural cells in leprosy.
Journal of neuropathology and experimental neurology
Petito RB,Amadeu TP,Pascarelli BM,Jardim MR,Vital RT,Antunes SL,Sarno EN
PA5-16793 was used in immunohistochemistry to study the role of TGF-beta1 in driving Schwann cell phenotypic reprogramming and fibrogenesis in response to Mycobacterium leprae
Mon Apr 01 00:00:00 EDT 2013
Low-grade fibromyxoid sarcoma with prominent giant rosettes and heterotopic ossification.
Pathology, research and practice
Hisaoka M,Matsuyama A,Aoki T,Sakamoto A,Yokoyama K
PA5-16793 was used in immunohistochemistry to report on a case of low-grade fibromyxoid sarcoma displaying unusual clinicopathology
Sat Sep 15 00:00:00 EDT 2012
Differences in metabolism between adeno- and squamous cell non-small cell lung carcinomas: spatial distribution and prognostic value of GLUT1 and MCT4.
Lung cancer (Amsterdam, Netherlands)
Meijer TW,Schuurbiers OC,Kaanders JH,Looijen-Salamon MG,de Geus-Oei LF,Verhagen AF,Lok J,van der Heijden HF,Rademakers SE,Span PN,Bussink J
PA5-16793 was used in immunohistochemistry to study the differential immunohistochemical expression of Glut1 and MCT4 in adeno and squamous cell non-small cell lung carcinoma and the metabolic significance
Fri Jun 01 00:00:00 EDT 2012
FDG-PET is a good biomarker of both early response and acquired resistance in BRAFV600 mutant melanomas treated with vemurafenib and the MEK inhibitor GDC-0973.
EJNMMI research
Baudy AR,Dogan T,Flores-Mercado JE,Hoeflich KP,Su F,van Bruggen N,Williams SP
PA5-16793 was used in immunohistochemistry to study FDG uptake as a biomarker of early response and acquired resistance in BRAFV600 mutant melanomas treated with vemurafenib and a MEK inhibitor
Thu May 31 00:00:00 EDT 2012
Correlation between FDG uptake by PET/CT and the expressions of glucose transporter type 1 and hexokinase II in cervical cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Tong SY,Lee JM,Ki KD,Choi YJ,Seol HJ,Lee SK,Huh CY,Kim GY,Lim SJ
PA5-16793 was used in immunohistochemistry to study the relationship between labelled glucose uptake and Glut1 and hexokinase II expression in lymph nodes of patients with cervical cancer
Tue May 01 00:00:00 EDT 2012
Targeting Glut1-overexpressing MDA-MB-231 cells with 2-deoxy-D-g1ucose modified SPIOs.
European journal of radiology
Shan XH,Hu H,Xiong F,Gu N,Geng XD,Zhu W,Lin J,Wang YF
PA5-16793 was used in immunocytochemistry to study the ability of 2-deoxy-D-glucose-modified SPIOs to target Glut1-overexpressing MDA-MB-231 tumor cells
Sun Jan 01 00:00:00 EST 2012
Biological factors, tumor growth kinetics, and survival after metastasectomy for pulmonary melanoma.
Annals of surgical oncology
Lee JH,Gulec SA,Kyshtoobayeva A,Sim MS,Morton DL
PA5-16793 was used in immunohistochemistry to investigate the prognostic markers for the development of pulmonary melanoma metastases after metastasectomy
Thu Oct 01 00:00:00 EDT 2009
The Warburg effect is genetically determined in inherited pheochromocytomas.
PloS one
Favier J,Brière JJ,Burnichon N,Rivière J,Vescovo L,Benit P,Giscos-Douriez I,De Reyniès A,Bertherat J,Badoual C,Tissier F,Amar L,Libé R,Plouin PF,Jeunemaitre X,Rustin P,Gimenez-Roqueplo AP
PA5-16793 was used in immunohistochemistry to investigate the mechanism of Warburg effect regulation in pheochromocytomas
Fri Sep 18 00:00:00 EDT 2009
Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells.
Cancer research
Ader I,Brizuela L,Bouquerel P,Malavaud B,Cuvillier O
PA5-16793 was used in western blot to investigate the role of sphingosine kinase 1 during hypoxia in human cancer cells
Wed Oct 15 00:00:00 EDT 2008
Human monocyte-derived hemangioma-like endothelial cells: evidence from an in vitro study.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
Jia J,Huang X,Zhang WF,Zhao YF
PA5-16793 was used in immunocytochemistry to investigate the pathogenesis of hemangioma
Tue Sep 30 00:00:00 EDT 2008
Correlation between FDG uptake and glucose transporter type 1 expression in neuroendocrine tumors of the lung.
Lung cancer (Amsterdam, Netherlands)
Song YS,Lee WW,Chung JH,Park SY,Kim YK,Kim SE
PA5-16793 was used in immunohistochemistry to investigate the association between FDG uptake and glucose transporter type 1
Tue Jul 01 00:00:00 EDT 2008
