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Proteintech
GLUT2 Polyclonal Antibody
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Product Details
20436-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GLUT2 Fusion Protein Ag14204 (69-128 aa encoded by BC060041)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody detected 60-70 kDa fully glycosylated, matured GLUT2 and a nonglycosylated form of GLUT2 around 38-45 kDa.
Immunogen sequence: SPRYLYIKL DEEVKAKQSL KRLRGYDDVT KDINEMRKER EEASSEQKVS IIQLFTNSSY R (69-128 aa encoded by BC060041)
Target Information
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in the gene that encode this protein cause Fanconi-Bickel syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glucose transporter 2; Glucose transporter type 2, liver; GLUT-2; liver-type glucose transporter; solute carrier family 2 (facilitated glucose transporter), member 2; Solute carrier family 2, facilitated glucose transporter member 2
Gene Aliases: AI266973; Glut-2; GLUT2; GTT2; SLC2A2
UniProt ID: (Human) P11168, (Mouse) P14246
Entrez Gene ID: (Human) 6514, (Mouse) 20526, (Rat) 25351
insulin receptor binding
glucose transmembrane transporter activity
hexose transmembrane transporter activity
dehydroascorbic acid transporter activity
D-glucose transmembrane transporter activity
transporter activity
sugar:proton symporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
transport
carbohydrate transport
carbohydrate utilization
glucose transport
proton transport
carbohydrate transmembrane transport
hexose transmembrane transport
glucose import
transmembrane transport
dehydroascorbic acid transport
cation transmembrane transport
carbohydrate metabolic process
hexose transport
response to glucose
fructose transport
response to peptide hormone
regulation of insulin secretion
glucose transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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