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Invitrogen
GLUT4 Polyclonal Antibody
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GLUT4 Antibody (PA5-19333) in IHC (P)
Immunohistochemistry analysis of GLUT4 in human skeletal muscle. Samples were incubated with GLUT4 polyclonal antibody (Product # PA5-19333) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-19333
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (TELEYLGPDEND) corresponding to the C-terminus amino acids of SLC2A4 (aa 498-509).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, human and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glucose transporter glut4; Glucose transporter type 4, insulin-responsive; GLUT-4; GT2; insulin-responsive glucose transporter type 4; MGC93607; solute carrier family 2 (facilitated glucose transporter), member 4; Solute carrier family 2, facilitated glucose transporter member 4
Gene Aliases: Glut-4; GLUT4; SLC2A4
UniProt ID: (Human) P14672, (Mouse) P14142
Entrez Gene ID: (Human) 6517, (Mouse) 20528
carbohydrate metabolic process
amylopectin biosynthetic process
glucose transport
cellular response to insulin stimulus
glucose homeostasis
response to ethanol
glucose import
brown fat cell differentiation
cellular response to hypoxia
cellular response to osmotic stress
glucose transmembrane transport
transport
carbohydrate transport
proton transport
hexose transmembrane transport
transmembrane transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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