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Invitrogen
GLUT4 Polyclonal Antibody
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FIGURE: 1 / 3
GLUT4 Antibody (PA5-80021) in IHC (P)
Immunohistochemical analysis of GLUT4 in paraffin-embedded section of human mammary cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-GLUT4 antibody (Product # PA5-80021) overnight at 4°C. Biotinylated goat anti-rabbit ... View More
Product Details
PA5-80021
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human GLUT4 (491-509aa EQEVKPSTELEYLGPDEND).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Cardiac Muscle Tissue, Rat Skeletal Muscle Tissue, Mouse Cardiac Muscle Tissue, Mouse Skeletal Muscle Tissue, HELA whole cell. IHC: Rat Cardiac Muscle Tissue, human mammary cancer tissue.
Target Information
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glucose transporter 4 insuline-responsive; Glucose transporter 4, insuline-responsive; glucose transporter glut4; Glucose transporter type 4, insulin-responsive; GLUT-4; GT2; insulin responsive glucose transporter; insulin-responsive glucose transporter type 4; MGC93607; solute carrier family 2 member 4; solute carrier family 2 (facilitated glucose transporter), member 4; solute carrier family 2 , member 4; Solute carrier family 2, facilitated glucose transporter member 4
Gene Aliases: Glut-4; GLUT4; SLC2A4
UniProt ID: (Human) P14672, (Rat) P19357, (Mouse) P14142
Entrez Gene ID: (Human) 6517, (Rat) 25139, (Mouse) 20528
amylopectin biosynthetic process
glucose transport
cellular response to insulin stimulus
hexose transmembrane transport
glucose homeostasis
response to ethanol
brown fat cell differentiation
transmembrane transport
cellular response to hypoxia
cellular response to osmotic stress
carbohydrate metabolic process
glucose import
glucose transmembrane transport
transport
carbohydrate transport
proton transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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