Search
Invitrogen
GLUT4 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-80022
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human GLUT4 recombinant protein (Position: N333-D509).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL once reconstituted
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat cardiac muscle tissue, rat skeletal muscle tissue. IHC: human intestinal cancer tissue, rat cardiac muscle tissue, mouse skeletal muscle tissue IHC-F: rat cardiac muscle tissue, mouse cardiac muscle tissue.
Target Information
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glucose transporter 2; glucose transporter 4 insulin-responsive; Glucose transporter 4, insuline-responsive; glucose transporter glut4; glucose transporter type 4, insulin-responsive; GLUT-4; insulin responsive glucose transporter; insulin-responsive glucose transporter; insulin-responsive glucose transporter type 4; MGC93607; solute carrier family 2 (facilitated glucose transporter), member 4; solute carrier family 2 , member 4; unnamed protein product
Gene Aliases: Glut-4; GLUT4; GT2; twgy
UniProt ID: (Human) P14672, (Mouse) P14142, (Rat) P19357
Entrez Gene ID: (Human) 6517, (Mouse) 20528, (Rat) 25139
learning or memory
short-term memory
long-term memory
amylopectin biosynthetic process
positive regulation of brain-derived neurotrophic factor receptor signaling pathway
cellular response to insulin stimulus
glucose homeostasis
glucose import in response to insulin stimulus
response to ethanol
brown fat cell differentiation
transmembrane transport
dehydroascorbic acid transport
cellular response to tumor necrosis factor
cellular response to hypoxia
cellular response to osmotic stress
regulation of synaptic vesicle budding from presynaptic endocytic zone membrane
glucose import across plasma membrane
glucose transmembrane transport
carbohydrate metabolic process
white fat cell proliferation
transport across blood-brain barrier
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support