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Invitrogen
GM-CSF Polyclonal Antibody, Biotin
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Product Details
PA1-84988
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein GM-CSF.
Conjugate
Form
Lyophilized
Concentration
0.1 mg/mL
Amount
50 µg
Storage conditions
4°C
Shipping conditions
Wet ice
RRID
Product Specific Information
Reconstitute with 0.5 mL PBS containing 0.1% BSA. For long term storage the addition of 0.09% sodium azide is recommended. PA1-84988 has a IgG concentration of ~0.1 mg/mL after reconstitution. Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles.
This antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA with PA1-84972 as the capture antibody.
Target Information
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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