The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
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Protein Aliases: beta c; beta common cytokine receptor; CD antigen CD131; CD131; CD131 antigen; CDw131; colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); Colony-stimulating factor 2 receptor subunit beta-2; colony-stimulating factor-2 receptor, beta, low-affinity; common beta chain; Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL-3 receptor class 2 subunit beta; IL-3R class 2 subunit beta; IL3R beta; interleukin 3 common beta chain; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); Interleukin-3 receptor class 2 subunit beta; Interleukin-3 receptor class II beta chain
Gene Aliases: Ai2ca; AI848964; AIC2A; AIC2B; Bc; BetaIl3; Bil3; CD131; CDw131; CSF2RB; Csf2rb1; Csf2rb2; Csfgmrb; Il3r; IL3RB; Il3rb1; Il3rb2; IL5RB; SMDP5
Molecular Function: transmembrane signal receptor