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Invitrogen
GNA12 Polyclonal Antibody
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Product Details
PA5-67775
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human GNA12.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 subunits; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G alpha-12; G protein; G-protein subunit alpha-12; guanine nucleotide binding protein (G protein) alpha 12; guanine nucleotide binding protein, alpha 12; Guanine nucleotide-binding protein subunit alpha-12; heterotrimeric guanine nucleotide-binding protein 1M1; unnamed protein product; WUGSC:H_GS165O14.2
Gene Aliases: AI414047; AI504261; Galpha12; gep; Gna-12; GNA12; HG1M1; NNX3; RMP
UniProt ID: (Human) Q03113, (Mouse) P27600, (Rat) Q63210
Entrez Gene ID: (Human) 2768, (Mouse) 14673, (Rat) 81663
nucleotide binding
G-protein coupled receptor binding
GTPase activity
obsolete small monomeric GTPase activity
protein binding
GTP binding
guanyl nucleotide binding
G-protein beta/gamma-subunit complex binding
D5 dopamine receptor binding
metal ion binding
protein phosphatase 2A binding
protein phosphatase activator activity
signal transducer activity
heterotrimeric G-protein
in utero embryonic development
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
Rho protein signal transduction
blood coagulation
regulation of blood pressure
regulation of cell shape
response to xenobiotic stimulus
regulation of fibroblast migration
cell differentiation
regulation of TOR signaling
regulation of proteasomal ubiquitin-dependent protein catabolic process
intracellular signal transduction
embryonic digit morphogenesis
Rho-activating G protein-coupled receptor signaling pathway
negative regulation of vascular smooth muscle cell proliferation
negative regulation of vascular associated smooth muscle cell migration
small GTPase mediated signal transduction
dopamine receptor signaling pathway
metabolic process
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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