This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
MA5-12800 targets Galphai1 G-Protein in WB applications and shows reactivity with Bovine, Guinea Pig, Human, mouse, and Rat samples.
The MA5-12800 immunogen is partially purified rat brain Galphai1 protein.
Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain; and transducin-1 and transducin-2, proteins involved in phototransduction in retinal rods and cones, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adenylate cyclase-inhibiting G alpha protein; Gi1 protein alpha subunit; Gi1 protein alpha-subunit; guanine nucleotide binding protein (G protein), alpha inhibiting 1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide binding protein, alpha inhibiting 1; Guanine nucleotide-binding protein G(i) subunit alpha-1; guanine nucleotide-binding protein G(i), alpha-1 subunit; p-alpha-h subunit; unnamed protein product
Gene Aliases: AU046200; BPGTPB; Gi; Gialpha1; Gnai-1; GNAI1
Molecular Function: heterotrimeric G-protein