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Invitrogen
GNAT1 Polyclonal Antibody
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FIGURE: 1 / 3
GNAT1 Antibody (PA5-28336) in IHC (F)
Immunohistochemistry (Frozen) analysis of GNAT1 was performed in frozen sectioned adult mouse retina tissue using GNAT1 Polyclonal Antibody (Product # PA5-28336) at a dilution of 1:250 (Green). Red: beta Tubulin 3/ TUJ1, stained by beta Tubulin 3/ TUJ1 antibody diluted at 1:250. Blue: Fluoroshield with DAPI.
Product Details
PA5-28336
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human GNAT1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.34 mg/mL
Amount
134 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: NT2D1, IMR32, U87-MG, mouse eye.
Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (92%), Xenopus laevis (92%), Dog (99%), Chicken (96%), Bovine (98%), Guinea pig (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein; guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; Guanine nucleotide-binding protein G(t) subunit alpha-1; guanine nucleotide-binding protein G(T), alpha-1 subunit; heterotrimeric guanine nucleotide-binding protein 1F; rod-type transducin alpha subunit; Tr alpha; Transducin alpha-1 chain; transducin, rod-specific; unnamed protein product
Gene Aliases: CSNB1G; CSNBAD3; GBT1; Gnat-1; GNAT1; GNATR; HG1F; Ird1; Ird2; irdc; irdr; Tralpha; transducin
UniProt ID: (Human) P11488, (Mouse) P20612
Entrez Gene ID: (Human) 2779, (Mouse) 14685
detection of chemical stimulus involved in sensory perception of bitter taste
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
visual perception
phototransduction
phototransduction, visible light
visual behavior
cell proliferation
response to light stimulus
detection of light stimulus
response to light intensity
dopamine secretion
rhodopsin mediated signaling pathway
regulation of rhodopsin mediated signaling pathway
eye photoreceptor cell development
retinal cone cell differentiation
detection of light stimulus involved in visual perception
sensory perception of umami taste
negative regulation of cyclic-nucleotide phosphodiesterase activity
retina development in camera-type eye
retinal rod cell differentiation
cellular response to electrical stimulus
neural tissue regeneration
background adaptation
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
response to stimulus
positive regulation of cyclic-nucleotide phosphodiesterase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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