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Invitrogen
GNAZ Polyclonal Antibody
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FIGURE: 1 / 2
GNAZ Antibody (PA5-99154) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded GNAZ in human brain tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with GNAZ polyclonal antibody (Product # PA5-99154) using a dilution of 1:200 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-99154
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GNAZ(Accession P19086), corresponding to amino acid residues M1-S42.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Gz alpha.
Target Information
GNAZ is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systems. This protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein; G(x) alpha chain; GNAZ; guanine nucleotide binding protein (G protein), alpha z polypeptide; Guanine nucleotide binding protein alpha; guanine nucleotide binding protein, alpha z polypeptide; guanine nucleotide binding protein, alpha z subunit; Guanine nucleotide-binding protein G(z) subunit alpha; Gz-alpha; heterotrimeric guanine nucleotide-binding protein 1H; transducin alpha; transducin alpha-subunit; unnamed protein product
Gene Aliases: AI847979; GNAZ; GXA; Gz; gz-alpha; HG1H
UniProt ID: (Human) P19086, (Mouse) O70443, (Rat) P19627
Entrez Gene ID: (Human) 2781, (Mouse) 14687, (Rat) 25740
nucleotide binding
G-protein coupled receptor binding
GTPase activity
protein binding
GTP binding
adenylate cyclase inhibitor activity
guanyl nucleotide binding
G-protein beta/gamma-subunit complex binding
G-protein coupled serotonin receptor binding
metal ion binding
signal transducer activity
heterotrimeric G-protein
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of insulin secretion
G protein-coupled serotonin receptor signaling pathway
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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