FIGURE: 1 / 7
Immunogen sequence: MSELEQLRQ EAEQLRNQIR DARKACGDST LTQITAGLDP VGRIQMRTRR TLRGHLAKIY AMHWGTDSRL LVSASQDGKL IIWDSYTTNK VHAIPLRSSW VMTCAYAPSG NFVACGGLDN ICSIYSLKTR EGNVRVSREL PGHTGYLSCC RFLDDNQIIT SSGDTTCALW DIETGQQTVG FAGHSGDVMS LSLAPDGRTF VSGACDASIK LWDVRDSMCR QTFIGHESDI NAVAFFPNGY AFTTGSDDAT CRLFDLRADQ ELLMYSHDNI ICGITSVAFS RSGRLLLAGY DDFNCNIWDA MKGDRAGVLA GHDNRVSCLG VTDDGMAVAT GSWDSFLKIW N (1-340 aa encoded by BC010073)
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein subunit beta-2; G protein, beta-2 subunit; guanine nucleotide binding protein (G protein), beta 2; guanine nucleotide binding protein (G protein), beta polypeptide 2; guanine nucleotide binding protein beta 2 subunit; guanine nucleotide binding protein, beta 2; guanine nucleotide binding protein, beta polypeptide 2; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; guanine nucleotide-binding protein, beta 2; guanine nucleotide-binding protein, beta-2 subunit; signal-transducing guanine nucleotide-binding regulatory protein beta subunit; Transducin beta chain 2
Gene Aliases: Gnb-2; GNB2
Molecular Function: heterotrimeric G-protein