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Proteintech
GNB3 Polyclonal Antibody
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Product Details
15388-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GNB3 Fusion Protein Ag7050 (3-340 aa encoded by BC002454)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Amount
67.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EMEQLRQEA EQLKKQIADA RKACADVTLA ELVSGLEVVG RVQMRTRRTL RGHLAKIYAM HWATDSKLLV SASQDGKLIV WDSYTTNKVH AIPLRSSWVM TCAYAPSGNF VACGGLDNMC SIYNLKSREG NVKVSRELSA HTGYLSCCRF LDDNNIVTSS GDTTCALWDI ETGQQKTVFV GHTGDCMSLA VSPDFNLFIS GACDASAKLW DVREGTCRQT FTGHESDINA ICFFPNGEAI CTGSDDASCR LFDLRADQEL ICFSHESIIC SITSVAFSLS GRLLFAGYDD FNCNVWDSMK SERVGILSGH DNRVSCLGVT ADGMAVATGS WDSFLKIWN (3-340 aa encoded by BC002454 )
Target Information
Heterotrimeric guanine nucleotide-binding proteins in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein beta 3; G protein beta-subunit; G protein, beta-3 subunit; gbb3; GTP-binding regulatory protein beta-3 chain; guanine nucleotide binding protein (G protein), beta 3; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide binding protein beta-3 subunit; guanine nucleotide binding protein, beta 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; guanine nucleotide-binding protein, beta-3 subunit; heterotrimeric guanine nucleotide-binding protein 2D; hypertension associated protein; Transducin beta chain 3
Gene Aliases: CSNB1H; Gnb-3; GNB3; HG2D
UniProt ID: (Human) P16520, (Mouse) Q61011, (Rat) P52287
Entrez Gene ID: (Human) 2784, (Mouse) 14695, (Rat) 60449
cell volume homeostasis
signal transduction
G-protein coupled receptor signaling pathway
regulation of blood pressure
regulation of gene expression
regulation of glucose metabolic process
regulation of hormone metabolic process
regulation of fat cell differentiation
regulation of feeding behavior
regulation of cholesterol metabolic process
regulation of triglyceride metabolic process
regulation of locomotion involved in locomotory behavior
regulation of phospholipid metabolic process
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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