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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
Immunohistochemistry (IHC) |
1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human GNG5(Accession P63218), corresponding to amino acid residues D46-S66. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2853210 |
G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327];Summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein gamma-5 subunit; guanine nucleotide binding protein (G protein), gamma 5; guanine nucleotide binding protein (G protein), gamma 5 subunit; guanine nucleotide binding protein gamma 5; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Gene Aliases: G(y)5; GNG5; GNGT5
UniProt ID: (Human) P63218, (Mouse) Q80SZ7, (Rat) P63219
Entrez Gene ID: (Human) 2787, (Mouse) 14707, (Rat) 79218
Molecular Function:
heterotrimeric G-protein
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