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This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 77%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 85%; Sheep: 77%
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
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Protein Aliases: G gamma-C; G protein cone gamma 8 subunit; G-gamma-8; G-gamma-9; gamma-T2 subunit; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; guanine nucleotide binding protein gamma 9; Guanine nucleotide binding protein gamma transducing activity polypeptide 2; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Gene Aliases: G-GAMMA-8; G-GAMMA-C; GNG8; GNG9; GNGT2; GNGT8
UniProt ID: (Human) O14610
Entrez Gene ID: (Human) 2793
Molecular Function: heterotrimeric G-protein