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Proteintech
GNPDA1 Polyclonal Antibody
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Product Details
12312-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GNPDA1 Fusion Protein Ag2961 (1-289 aa encoded by BC012853)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKLIILEHY SQASEWAAKY IRNRIIQFNP GPEKYFTLGL PTGSTPLGCY KKLIEYYKNG DLSFKYVKTF NMDEYVGLPR DHPESYHSFM WNNFFKHIDI HPENTHILDG NAVDLQAECD AFEEKIKAAG GIELFVGGIG PDGHIAFNEP GSSLVSRTRV KTLAMDTILA NARFFDGELT KVPTMALTVG VGTVMDAREV MILITGAHKA FALYKAIEEG VNHMWTVSAF QQHPRTVFVC DEDATLELKV KTVKYFKGLM LVHNKLVDPL YSIKEKETEK SQSSKKPYSD (1-289 aa encoded by BC012853)
Target Information
GNPDA1 is a 289 amino acid cytoplasmic protein belonging to the glucosamine/ galactosamine-6-phosphate isomerase family. It is one of the two mammalian glucosamine-6-phosphate deaminase enzymes. GNPDA1 is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate (GlcN6P) into D-fructose-6-phosphate (Fru6P) and ammonium with an aldo/keto isomerization and an amination/deamination. GNPDA1 may trigger calcium oscillations in mammalian eggs at fertilization which in turn serve as an important factor for egg development and early embryo development. It is a homohexamer, ubiquitously expressed in most of human tissues with high expression in testis, ovary, placenta, and heart and also in various cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GlcN6P deaminase 1; Glucosamine-6-phosphate deaminase 1; Glucosamine-6-phosphate isomerase 1; glucose-6-phosphate isomerase; GNPDA 1; KIAA0060; oscillin; Protein oscillin; sperm factor; unnamed protein product
Gene Aliases: GNP1; GNPDA; GNPDA1; GNPI; GPI; HLN; KIAA0060; oscillin
UniProt ID: (Human) P46926, (Mouse) O88958
Entrez Gene ID: (Human) 10007, (Mouse) 26384, (Rat) 683570
carbohydrate metabolic process
glucosamine catabolic process
N-acetylglucosamine metabolic process
N-acetylglucosamine catabolic process
UDP-N-acetylglucosamine biosynthetic process
generation of precursor metabolites and energy
single fertilization
N-acetylneuraminate catabolic process
fructose 6-phosphate metabolic process
glucosamine metabolic process
acrosome reaction
fructose biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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