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Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: TPQDVLRASQ GKSVTLPCTY HTSTSSREGL IQWDKLLLTH TERVVIWPFS NKNYIHGELY KNRVSISNNA EQSDASITID QLTMADNGTY ECSVSLMSDL EGNTKSRVRL LVLVPPSKPE CGIEGETIIG NNIQLTCQSK EGSPTPQYSW KRYNILNQEQ PLAQPASGQP VSLKNISTDT SGYYICTSSN EEGTQFCNIT VAVRSPSMNV ALYVGIAVGV VAALIIIGII IYCCCCRGKD DNTEDKEDAR PNREAYEEPP EQLRELSRER EEEDDYRQEE QRSTGRESPD HLDQ
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A33 antigen; Cell surface A33 antigen; Glycoprotein A33; glycoprotein A33 (transmembrane); mA33; MGC129986; MGC129987; transmembrane glycoprotein A33
Gene Aliases: 2010310L10Rik; 2210401D16Rik; A33; BB116197; GPA33
UniProt ID: (Human) Q99795, (Mouse) Q9JKA5
Entrez Gene ID: (Human) 10223, (Mouse) 59290
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