Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse brain.
Predicted reactivity: Mouse (92%), Rat (91%), Zebrafish (85%), Chicken (86%), Sheep (92%), Rhesus Monkey (98%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
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Protein Aliases: brain form; glycogen phosphorylase; glycogen phosphorylase B; Glycogen phosphorylase, brain form; GPBB
Gene Aliases: GPBB; PYGB