G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
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Protein Aliases: fatty acid receptor 2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; Leukocyte-specific STAT-induced GPCR
Gene Aliases: FFA2; FFA2R; FFAR2; GPCR43; GPR43; Lssig