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Invitrogen
GPD1L Polyclonal Antibody
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FIGURE: 1 / 1
GPD1L Antibody (PA5-114389) in WB
Western blot analysis of GPD1L in the following samples: Lane 1: human placenta issue lysates, Lane 2: human PC-3 whole cell lysates, Lane 3: human U-87MG whole cell lysates, Lane 4: human HL-60 whole cell lysates, Lane 5: human HepG2 whole cell lysates, Lane 6: human A549 whole cell lysates, Lane 7: human Caco-2 whole cell lysates, Lane 8: human K562 whole cell lysates, Lane 9: rat heart issue lysates, Lane 10: mouse RAW246.7 whole cell lysates. Samples consisting of 50 µg (reducing conditions) of protein was separated with 5-20% SDS-PAGE... View More
Product Details
PA5-114389
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human GPD1L recombinant protein (Position: A19-T351).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta issue, human PC-3 whole cell, human U-87MG whole cell, human HL-60 whole cell, human HepG2 whole cell, human A549 whole cell, human Caco-2 whole cell, human K562 whole cell, rat heart issue, mouse RAW2467 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glycerol-3-phosphate dehydrogenase 1-like protein; GPD1-L; KIAA0089; unnamed protein product
Gene Aliases: 2210409H23Rik; D9Ertd660e; GPD1-L; GPD1L; KIAA0089; RGD1560123
UniProt ID: (Human) Q8N335, (Mouse) Q3ULJ0
Entrez Gene ID: (Human) 23171, (Mouse) 333433, (Rat) 363159
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
sodium channel regulator activity
protein homodimerization activity
ion channel binding
glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NAD binding
glycerol-3-phosphate dehydrogenase [NAD+] activity
molecular_function
dehydrogenase
regulation of heart rate
carbohydrate metabolic process
glycerol-3-phosphate metabolic process
positive regulation of sodium ion transport
NAD metabolic process
glycerol-3-phosphate catabolic process
regulation of ventricular cardiac muscle cell membrane depolarization
ventricular cardiac muscle cell action potential
positive regulation of protein localization to cell surface
NADH metabolic process
negative regulation of peptidyl-serine phosphorylation
oxidation-reduction process
negative regulation of protein kinase C signaling
regulation of sodium ion transmembrane transporter activity
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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