Suggested positive control: mouse kidney lysate or protein.
GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.
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Protein Aliases: Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; GlycosylPhosphatidylInositol-anchored high-de; GPI-anchored HDL-binding protein 1; GPI-anchored HDL-binding protein 1 antibody; GPI-anchored High-Density Lipid-binding protein 1 antibody; GPI-HBP1; gpihbp1; High density lipoprotein-binding protein 1
Gene Aliases: 1110002J19Rik; GPI-HBP1; Gpihbp1; Hbp1; RGD1564237
UniProt ID: (Mouse) Q9D1N2