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PA1-41622 detects GPR109B in chimpanzee and human samples.
This antibody is predicted to react with canine and hamster based on sequence homology.
The amino acid sequence used as immunogen is 86% in Rhesus Macaque.
Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GTP-binding protein; hydroxy-carboxylic acid receptor 3; Hydroxycarboxylic acid receptor 3; Niacin receptor 2; Nicotinic acid receptor 2; putative chemokine receptor; unnamed protein product
Gene Aliases: GPR109B; HCA3; HCAR3; HM74; HM74B; NIACR2; Puma-g; PUMAG
UniProt ID: (Human) P49019
Entrez Gene ID: (Human) 8843
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