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Product Details
PA5-32793
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from 1st extracellular domain of human GPR12 / GPCR12.
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550255
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Pig, Opossum (100%); Bat, Elephant, Rabbit (94%); Turkey, Chicken (88%); Platypus, Xenopus (81%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ18149; FLJ97704; G protein-coupled receptor 12; G-protein coupled receptor 12; GPCR01; MGC138349; MGC138351; protein phosphatase 1, regulatory subunit 84; R334
Gene Aliases: Gpcr01; GPCR12; Gpcr20; GPCR21; GPR12; PPP1R84
UniProt ID: (Human) P47775, (Mouse) P35412, (Rat) P30951
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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