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Product Details
17026-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GPR132 Fusion Protein Ag10325 (214-380 aa encoded by BC084546)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IIAFTNHRI FRSIKQSMGL SAAQKAKVKH SAIAVVVIFL VCFAPYHLVL LVKAAAFSYY RGDRNAMCGL EERLYTASVV FLCLSTVNGV ADPIIYVLAT DHSRQEVSRI HKGWKEWSMK TDVTRLTHSR DTEELQSPVA LADHYTFSRP VHPPGSPCPA KRLIEESC (214-380 aa encoded by BC084546)
Target Information
GPCR G2A is a G-protein linked receptor for lysophosphatidylcholine (LPC). It may play a role as a sensor of LPC levels at sites of inflammation to limit tissue-infiltrating-cells and progression to overt autoimmune disease and functions at the G2/M checkpoint to delay mitosis. It also may serve as a mechanism for T and B cells, and other cell types, to slow their proliferation and repair damaged DNA. It is highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus, but weakly expressed in heart and lung. In atherosclerotic plaques, expression was observed around the lipid core and at the shoulder region. It is induced by DNA-damaging agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein-coupled receptor G2A; G2 accumulation protein; MGC99642; Probable G-protein coupled receptor 132
Gene Aliases: G2A; GPR132
UniProt ID: (Human) Q9UNW8, (Mouse) Q9Z282
Entrez Gene ID: (Human) 29933, (Mouse) 56696, (Rat) 314480
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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