|Immunohistochemistry (Paraffin) (IHC (P))||6 - 14 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from C-terminus of human GPR143.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Monkey, Marmoset (88%).
Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor 143; G-protein coupled receptor 143; GPR143; NYS6; OA1; Ocular albinism 1; Ocular albinism type 1 protein
Gene Aliases: GPR143; NYS6; OA1
UniProt ID: (Human) P51810
Entrez Gene ID: (Human) 4935
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