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Invitrogen
GPR17 Polyclonal Antibody
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FIGURE: 1 / 1
GPR17 Antibody (PA3-005) in IHC (P)
Immunohistochemistry analysis of GPR17 was performed on human kidney tissue. To expose target proteins, antigen retrieval was performed by microwaving tissues for 20 minutes in 10mM sodium citrate buffer (pH 6.0). Tissue slides were probed with a GPR17 polyclonal antibody (Product # PA3-005) at a dilution of 1:3000, overnight at 4C in a humidified chamber. Tissues were washed, and detection was performed us... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA3-005
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated Cys-SFEGKTNESSLSAKSEL
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
IHC (P) analysis shows positive staining of GPR17 in human kidney tissue.
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686M18273; P2Y-like receptor; R12; UDP/CysLT receptor; unnamed protein product; Y12546; Z94155
UniProt ID: (Human) Q13304
Entrez Gene ID: (Human) 2840
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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