Proteintech

GPR177 Polyclonal Antibody

GPR177 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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GPR177 Antibody (17950-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse liver tissue slide using 17950-1-AP (GPR177 Antibody) at dilution of 1:200 (under 10x lens).

GPR177 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

17950-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GPR177 Fusion Protein Ag12428 (34-239 aa encoded by BC110826)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LIAPGPTTA VSYMSVKCVD ARKNHHKTKW FVPWGPNHCD KIRDIEEAIP REIEANDIVF SVHIPLPHME MSPWFQFMLF ILQLDIAFKL NNQIRENAEV SMDVSLAYRD DAFAEWTEMA HERVPRKLKC TFTSPKTPEH EGRYYECDVL PFMEIGSVAH KFYLLNIRLP VNEKKKINVG IGEIKDIRLV GIHQNGGFTK VWFAMKT (34-239 aa encoded by BC110826)

Target Information

Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.

Molecular cell

Wang L,Li J,Wang Q,Ge MX,Ji J,Liu D,Wang Z,Cao Y,Zhang Y,Zhang ZR

Thu Sep 15 00:00:00 UTC 2022

WNT5A Enhances LH-Mediated Expression of HAS2 in Granulosa Cells.

Reproductive sciences (Thousand Oaks, Calif.)

Niu Q,Shi J,Gao Q,Fu J

Sun May 01 00:00:00 UTC 2022

The effect of Wnt/β-catenin pathway on the scleral remolding in the mouse during form deprivation.

International ophthalmology

Hu S,Ouyang S,Liu H,Zhang D,Deng Z

Wed Sep 01 00:00:00 UTC 2021

A Longitudinal Study of T2 Mapping Combined With Diffusion Tensor Imaging to Quantitatively Evaluate Tissue Repair of Rat Skeletal Muscle After Frostbite.

Frontiers in physiology

Gao Y,Lu Z,Lyu X,Liu Q,Pan S

Fri Feb 12 00:00:00 UTC 2021

Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.

OncoTargets and therapy

Zheng D,Jiang C,Yan N,Miao Y,Wang K,Gao G,Jiao Y,Zhang X,He M,Yang Z

Tue Apr 19 00:00:00 UTC 2022

Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.

OncoTargets and therapy

Zheng D,Jiang C,Yan N,Miao Y,Wang K,Gao G,Jiao Y,Zhang X,He M,Yang Z

Tue Apr 19 00:00:00 UTC 2022

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat.

Cells

Wang S,Li F,Liu J,Zhang Y,Zheng Y,Ge W,Qu L,Wang X

Tue Apr 14 00:00:00 UTC 2020

Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs.

Cell research

Zhou C,Yang X,Sun Y,Yu H,Zhang Y,Jin Y

Mon Feb 01 00:00:00 UTC 2016

Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs.

Cell research

Zhou C,Yang X,Sun Y,Yu H,Zhang Y,Jin Y

Mon Feb 01 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: evenness interrupted homolog; EVI; G protein-coupled receptor 177; Integral membrane protein GPR177; Protein evenness interrupted homolog; Protein wntless homolog; Putative NF-kappa-B-activating protein 373; putative NFkB activating protein 373

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Gene Aliases: 5031439A09Rik; AI173978; AI987742; C1orf139; EVI; GPR177; mig-14; MRP; UNQ85/PRO18667; WLS

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UniProt ID: (Human) Q5T9L3, (Mouse) Q6DID7, (Rat) Q6P689

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Entrez Gene ID: (Human) 79971, (Mouse) 68151, (Rat) 362065

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Function(s)

signal transducer activity protein binding Wnt-protein binding mu-type opioid receptor binding

Process(es)

mesoderm formation multicellular organism development anterior/posterior axis specification Wnt signaling pathway positive regulation of canonical Wnt signaling pathway biological_process intracellular protein transport positive regulation of Wnt signaling pathway midbrain development hindbrain development exocrine pancreas development positive regulation of I-kappaB kinase/NF-kappaB signaling Wnt protein secretion positive regulation of Wnt protein secretion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GPR177 Polyclonal Antibody

GPR177 Antibody (17950-1-AP) in IHC (P)

Product Details

17950-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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