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Proteintech
GPR177 Polyclonal Antibody
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Product Details
17950-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GPR177 Fusion Protein Ag12428 (34-239 aa encoded by BC110826)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LIAPGPTTA VSYMSVKCVD ARKNHHKTKW FVPWGPNHCD KIRDIEEAIP REIEANDIVF SVHIPLPHME MSPWFQFMLF ILQLDIAFKL NNQIRENAEV SMDVSLAYRD DAFAEWTEMA HERVPRKLKC TFTSPKTPEH EGRYYECDVL PFMEIGSVAH KFYLLNIRLP VNEKKKINVG IGEIKDIRLV GIHQNGGFTK VWFAMKT (34-239 aa encoded by BC110826)
Target Information
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: evenness interrupted homolog; EVI; G protein-coupled receptor 177; Integral membrane protein GPR177; Protein evenness interrupted homolog; Protein wntless homolog; Putative NF-kappa-B-activating protein 373; putative NFkB activating protein 373; unnamed protein product; wntless Wnt ligand secretion mediator
Gene Aliases: 5031439A09Rik; AI173978; AI987742; C1orf139; EVI; GPR177; mig-14; MRP; UNQ85/PRO18667; WLS; ZKS
UniProt ID: (Human) Q5T9L3, (Mouse) Q6DID7, (Rat) Q6P689
Entrez Gene ID: (Human) 79971, (Mouse) 68151, (Rat) 362065
mesoderm formation
intracellular protein transport
anterior/posterior axis specification
Wnt signaling pathway
positive regulation of Wnt signaling pathway
midbrain development
hindbrain development
exocrine pancreas development
positive regulation of I-kappaB kinase/NF-kappaB signaling
Wnt protein secretion
positive regulation of Wnt protein secretion
cementum mineralization
positive regulation of canonical Wnt signaling pathway
multicellular organism development
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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