|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||COOH-terminal amino acids of mouse GPR20 (338–358) IHILSIGSHTLTQPLTNGPEP coupled to KLH|
|Storage buffer||whole serum|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:2000|
|Western Blot (WB)||1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA3-068 detects GPR20 from mouse samples.
PA3-068 has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures. By Western blot, this antibody detects a 39 kDa protein corresponding to mouse GPR20.
The PA3-068 antigen is the COOH-terminal amino acids of mouse GPR20 (338–358) IHILSIGSHTLTQPLTNGPEP coupled to KLH.
G protein-coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors (GPLR), comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and animals. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters, and vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases, and are also the target of approximately 30% of all modern medicinal drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.