|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||4 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPR27.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Rat (89%).
G protein coupled receptors (GPCRs) are a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins. The 375 amino acid GPCR GPR27 protein contains several features of the GPCR family, including 7 transmembrane domains, potential N linked glycosylation sites in the N terminal extracellular domain, and conserved cysteine residues, which may form a disulfide bridge, in the first and second extracellular loops.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor 27; GPR27; Probable G-protein coupled receptor 27; SREB1; Super conserved receptor expressed in brain 1
Gene Aliases: GPR27; SREB1
UniProt ID: (Human) Q9NS67
Entrez Gene ID: (Human) 2850
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