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Invitrogen
GPR4 Polyclonal Antibody
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Product Details
PA5-33711
Product Specifications
Species Reactivity
Dog,
Human,
Non-human primate,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR4.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Dog, Panda, Pig (100%) Bovine, Bat, Rabbit, Zebrafish (95%) Mouse, Rat (85%).
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPR4 is a member of this family (subfamily lysophospholipid/lysosphingolipid) and its expression has been reported in kidney, heart, and especially lung, where it is at least five-fold greater than in other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor 19; G-protein coupled receptor 4; G-protein coupled receptor 6C.l; Gpr6c; GPR6C.l; hGPR4; unnamed protein product
Gene Aliases: GPR4; GPR6C.l
UniProt ID: (Human) P46093, (Pig) P50132
Entrez Gene ID: (Human) 2828, (Pig) 100144489, (Dog) 484440
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
response to acidic pH
negative regulation of angiogenesis
regulation of cell adhesion
positive regulation of Rho protein signal transduction
regulation of vascular permeability
positive regulation of inflammatory response
angiogenesis involved in wound healing
cellular response to acidic pH
glomerular mesangial cell development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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