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Product Details
PA5-67931
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human GPR40.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2692018
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FFAR; Free fatty acid receptor 1; G protein-coupled receptor 40; G protein-coupled receptor GPR40; G-protein coupled receptor 40; HGNC:4498
Gene Aliases: FFA1R; FFAR1; GPCR40; GPR40
UniProt ID: (Human) O14842, (Rat) Q8K3T4, (Mouse) Q76JU9
Entrez Gene ID: (Human) 2864, (Rat) 266607, (Mouse) 233081
G-protein coupled receptor signaling pathway
positive regulation of calcium ion transport into cytosol
insulin secretion
positive regulation of insulin secretion
glucose homeostasis
positive regulation of calcium ion transport
response to fatty acid
signal transduction
positive regulation of GTPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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