In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset, Goat (81%).
Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FFA3R; FFAR3; Free fatty acid receptor 3; G protein-coupled receptor 41; G-protein coupled receptor 41; Gpcr41; GPR41; Gpr42
Gene Aliases: FFA3R; FFAR3; GPR41; GPR42
UniProt ID: (Human) O14843
Entrez Gene ID: (Human) 2865