In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Monkey (94%).
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
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Protein Aliases: fatty acid receptor 2; FFA2R; FFAR2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43; Gpcr43; GPR43; LSSIG
Gene Aliases: FFA2; FFA2R; FFAR2; GPCR43; GPR43
UniProt ID: (Human) O15552
Entrez Gene ID: (Human) 2867