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GPR85, a member of the SREB (Super-Conserved Receptor Expressed in Brain) family of GPCRs, is an Orphan-A GPCR with an unknown ligand. The rat counterpart of SREB2 is involved in the development of the cerebral cortex. GPR85 has been reported to be expressed in several areas of human and rat CNS (Matsumoto et al., 2000), as well as in genital organs. ESTs have been isolated from B-cell/lung/testis, brain, testis, and embryo libraries, as well as many mouse tissue libraries.
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Protein Aliases: brain super conserved receptor 2; FLJ50993; FLJ51159; FLJ99433; G protein-coupled receptor 85; PKrCx1; Probable G protein-coupled receptor 85; Probable G-protein coupled receptor 85; putative G-protein coupled receptor 85; Rgpr85; seven transmembrane helix receptor; SREB2; Super Conserved Receptor Expressed in Brain 2; zSREB2
Gene Aliases: 2900026B03Rik; GPR85; serb2; si:dkey-223l3.1; SREB; SREB2; Srep2; zSREB2
UniProt ID: (Human) P60893, (Mouse) P60894, (Rat) P60895, (Zebrafish) Q9I919
Entrez Gene ID: (Human) 54329, (Pig) 100736987, (Chicken) 417775, (Bovine) 504208, (Horse) 100055809, (Dog) 482410, (Rabbit) 100357476, (Chinese hamster) 100763062, (Mouse) 64450, (Rat) 64020, (Zebrafish) 793299
Molecular Function: G-protein coupled receptor transmembrane signal receptor
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