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Invitrogen
GPRC5B Polyclonal Antibody
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Product Details
PA5-33799
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GPRC5B.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-69G12.1; G protein-coupled receptor, class C, group 5, member B; G protein-coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 5, member B; G-protein coupled receptor family C group 5 member B; hypothetical protein, clone 2-63; RAIG-2; retinoic acid responsive gene protein; Retinoic acid-induced gene 2 protein
Gene Aliases: AW125761; GPRC5B; RAIG-2; RAIG2
UniProt ID: (Human) Q9NZH0, (Mouse) Q923Z0
Entrez Gene ID: (Human) 51704, (Horse) 100052112, (Bovine) 516334, (Rabbit) 100353261, (Dog) 100856475, (Mouse) 64297, (Rat) 293546
G-protein coupled receptor signaling pathway
locomotory behavior
positive regulation of neuron projection development
activation of protein kinase activity
glucose homeostasis
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of neuron differentiation
positive regulation of inflammatory response
positive regulation of macrophage cytokine production
positive regulation of protein tyrosine kinase activity
positive regulation of canonical Wnt signaling pathway
positive regulation of protein phosphorylation
signal transduction
positive regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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