PA5-27149 targets CSN1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27149 immunogen is synthetic peptide corresponding to a region within amino acids 430 and 491 of Human CSN1.
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This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: COP9 signalosome complex subunit 1; COPS1; CSN1; G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH; SGN1; signalosome subunit 1
Gene Aliases: COPS1; CSN1; GPS1; SGN1
UniProt ID: (Human) Q13098
Entrez Gene ID: (Human) 2873