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      GPS2 Polyclonal Antibody

      See 1 other GPS2 antibodies ›
      GPS2 Polyclonal Antibody for Western Blot, IF, ICC and IHC (P)

      Catalog#: PA5-30953 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-30953 100 µL
      349.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

      Anti-Rabbit Secondary Antibodies (264)
      Alexa Fluor® Anti-Rabbit Secondary Antibodies (69)
      HRP Anti-Rabbit Secondary Antibodies (30)

      Product Details

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen Recombinant protein fragment corresponding to a region within amino acids 1 and 253 of Human GPS2
      Conjugate Unconjugated
      Form Liquid
      Concentration 1 mg/ml
      Purification Antigen affinity chromatography
      Storage buffer PBS, pH 7, with 1% BSA, 20% glycerol
      Contains 0.01% thimerosal
      Storage Conditions -20° C, Avoid Freeze/Thaw Cycles
      Tested Applications Dilution *
      Immunocytochemistry (ICC) 1:500
      Immunofluorescence (IF) 1:500
      Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
      Western Blot (WB) 1:500-1:3000

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Product Specific Information

      PA5-30953 targets GPS2 in IHC (P) and WB applications and shows reactivity with Human samples.

      The PA5-30953 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 253 of Human GPS2.

      Background/Target Information

      This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      Documents

      Material safety data sheets (MSDS)

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