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Invitrogen
GPSM2 Polyclonal Antibody
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FIGURE: 1 / 3
GPSM2 Antibody (PA5-18646) in ICC/IF
Immunocytochemistry analysis of GPSM2 using GPSM2 Polyclonal Antibody (Product # PA5-18646) in paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
Product Details
PA5-18646
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (NRLKGKKYKTNSSTK) corresponding to the internal amino acids of GPSM2 (aa 448-463).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; GPSM2; HGNC:29501; LGN protein; Mosaic protein LGN; unnamed protein product
Gene Aliases: CMCS; DFNB82; GPSM2; LGN; PINS
UniProt ID: (Human) P81274
Entrez Gene ID: (Human) 29899
establishment of mitotic spindle orientation
mitotic spindle organization
G-protein coupled receptor signaling pathway
response to light intensity
cell division
maintenance of centrosome location
regulation of mitotic spindle organization
neurotransmitter receptor localization to postsynaptic specialization membrane
positive regulation of protein localization to cell cortex
positive regulation of spindle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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