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Invitrogen
GPX2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 8
GPX2 Antibody (PA5-27150) in ICC/IF
GPX2 Polyclonal Antibody detects GPX2 protein at granule by immunofluorescent analysis. Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GPX2 stained by GPX2 Polyclonal Antibody (Product # PA5-27150) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin Polyclonal Antibody [GT114] (Product # MA5-31466) diluted at 1:1,000. Blue: Fluoroshield with DAPI .
Product Details
PA5-27150
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 126 and 190 of Human GPX2
Conjugate
Unconjugated
Form
Liquid
Concentration
1.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2544626
Product Specific Information
Recommended positive controls: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Gastrointestinal glutathione peroxidase; Glutathione peroxidase 2; glutathione peroxidase 2 (gastrointestinal); Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP-2; GPx-2; GPx-GI; HGNC:4554; intestinal GPx
Gene Aliases: GI-GPx; GPRP; GPRP-2; GPx-2; GPx-GI; GPX2; GSHPx-2; GSHPX-GI
UniProt ID: (Human) P18283, (Mouse) Q9JHC0
Entrez Gene ID: (Human) 2877, (Mouse) 14776
Molecular Function:
peroxidase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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