Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: Jurkat.^M
^M
Predicted reactivity: Mouse (90%), Rat (92%), Rhesus Monkey (99%), Bovine (90%).^M
^M
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adapter protein GRID; GRB-2-like protein; GRB2-related adapter protein 2; GRB2-related protein with insert domain; GRB2L; GRBLG; GRBX; Grf-40; Grf40 adapter protein; Growth factor receptor-binding protein; growth factor receptor-bound protein 2-related adaptor protein 2; Hematopoietic cell-associated adapter protein GrpL; hematopoietic cell-associated adaptor protein GRPL; P38; Protein GADS; RP3-370M22.1; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule
Gene Aliases: GADS; GRAP-2; GRAP2; GRB2L; GRBLG; GrbX; Grf40; GRID; GRPL; Mona; P38
UniProt ID: (Human) O75791
Entrez Gene ID: (Human) 9402
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