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Invitrogen
GRB10 Polyclonal Antibody
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FIGURE: 1 / 1
GRB10 Antibody (PA5-79322) in IHC
Genes 2021 -
Figure 2 Expression of "embryo-high" imprinted genes in the developing and postnatal pituitary gland . In situ hybridisation (ISH) using antisense riboprobes against insulin growth factor 2 ( Igf2 ) ( A - G ), cyclin-dependent kinase inhibitor 1C ( Cdkn1c ) ( H - N ), neuronatin ( Nnat ) ( O - U ) and immunohistochemistry (IHC) against growth-factor receptor bound protein 10 (GRB10) ( V-Ac ) and sex-determi... View More
Product Details
PA5-79322
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human GRB10.
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
Product Specific Information
The synthetic peptide sequence is 550-567aa, DGQTFFSLDDGNTKFSD
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Target Information
GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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