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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence PRNYVTPVNRNV, from C Terminus of the protein sequence according to NP_002077|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-dependent|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31495 detects GRB2 from human samples.
PA1-31495 has been successfully used in Western blot applications.
The PA1-31495 immunogen is: Peptide with sequence PRNYVTPVNRNV, from C Terminus of the protein sequence according to NP_002077
GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2 - Sos complex then binds the EGF receptor. These interactions
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
abundant SRC homology; adapter protein GRB2; ASH protein; EGFRBP-GRB2; epidermal growth factor; epidermal growth factor receptor-binding protein GRB2; Grb3-3; Growth Factor Receptor-bound protein 2; growth factor receptor-bound protein 3; HT027; MST084; MSTP084; protein Ash; SH2/SH3 adapter GRB2
AA408164; ASH; EGFRBP-GRB2; GRB2; Grb3-3; MST084; MSTP084; NCKAP2