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Proteintech
GRIA3 Polyclonal Antibody
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Product Details
29588-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VRLDEREFPE AKNAPLKYTS ALTHDAILVI AEAFRYLRRQ RVDVSRRGSA GDCLANPAVP WSQGIDIERA LKMVQVQGMT GNIQFDTYGR RTNYTIDVYE MKVSGSRKAG YWNEYERFVP FSDQQISNDS ASSENRTI
Target Information
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMPA receptor subunit GluA3; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluR-3; GluR-C; GluR-K3; glutamate receptor; Glutamate receptor 3; glutamate receptor C; glutamate receptor channel alpha3 subunit; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA3 (alpha 3); OTTHUMP00000024262; RP11-349N19.3; unnamed protein product
Gene Aliases: 2900064I19Rik; GluA3; GluR-3; GLUR-C; GLUR-K3; GLUR3; Gluralpha3; GLURC; GRIA3; iGluR3; Kiaa4184; MRX94; MRXSW
UniProt ID: (Human) P42263, (Mouse) Q9Z2W9, (Rat) P19492
Entrez Gene ID: (Human) 2892, (Mouse) 53623, (Rat) 29628
beta-amyloid binding
ionotropic glutamate receptor activity
AMPA glutamate receptor activity
ion channel activity
ligand-gated ion channel activity
glutamate-gated calcium ion channel activity
signaling receptor activity
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
receptor activity
extracellular-glutamate-gated ion channel activity
protein binding
PDZ domain binding
transmembrane signal receptor
ion transport
glutamate receptor signaling pathway
calcium-mediated signaling
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
synaptic transmission, glutamatergic
modulation of synaptic transmission
protein homotetramerization
protein heterotetramerization
regulation of postsynaptic membrane potential
long-term synaptic potentiation
regulation of presynaptic membrane potential
regulation of receptor recycling
transport
response to lithium ion
response to fungicide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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