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Proteintech
GRIPAP1 Polyclonal Antibody
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Product Details
15806-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GRIPAP1 Fusion Protein Ag8540 (577-841 aa encoded by BC001522)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The MW of this protein is 97 kDa, and 15806-1-AP specifically recognizes the 97 kDa protein.
Immunogen sequence: QEERDCHLK TISSLKQEVK DTVDGQRILE KKGSAALKDL KRQLHLERKR ADKLQERLQD ILTNSKSRSG LEELVLSEMN SPSRTQTGDS SSISSFSYRE ILREKESSAV PARSLSSSPQ AQPPRPAELS DEEVAELFQR LAETQQEKWM LEEKVKHLEV SSASMAEDLC RKSAIIETYV MDSRIDVSVA AGHTDRSGLG SVLRDLVKPG DENLREMNKK LQNMLEEQLT KNMHLHKDME VLSQEIVRLS KECVGPPDPD LEPGETS (577-841 aa encoded by BC001522 )
Target Information
PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GRASP-1; GRIP-1; GRIP-associated protein 1; GRIP1; GRIP1-associated protein 1; HCMV-interacting protein; MPMGp800B12492Q3
Gene Aliases: AI854681; DXImx47e; GRASP-1; Grasp1; GRIPAP1; KIAA1167; mKIAA1167; Sfc10
UniProt ID: (Human) Q4V328, (Rat) Q9JHZ4, (Mouse) Q8VD04
Entrez Gene ID: (Human) 56850, (Rat) 116493, (Mouse) 54645
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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