Keep as concentrated solution.
Positive Control: H1299, Molt-4, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADRBK1 antibody; adrenergic; adrenergic beta receptor kinase 1; adrenergic, beta, receptor kinase 1; BARK1 antibody; beta; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 antibody; beta-AR kinase-1; Beta-ARK-1; beta-ARK-1 antibody; BETA-ARK1 antibody; FLJ16718 antibody; G-protein coupled receptor kinase 2; G-protein coupled receptor kinase 2 antibody; G-protein-coupled receptor kinase 2; GRK2 antibody; receptor kinase 1 antibody
Gene Aliases: Adrbk-1; ADRBK1; BARK; Bark-1; BARK1; beta ARK; BETA-ARK1; betaARK1; GRK2