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Proteintech
GRPEL2 Polyclonal Antibody
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Product Details
17751-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GRPEL2 Fusion Protein Ag12018 (1-225 aa encoded by BC070090)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAVRSLWAG RLRVQRLLAW SAAWESKGWP LPFSTATQRT AGEDCRSEDP PDELGPPLAE RALRVKAVKL EKEVQDLTVR YQRAIADCEN IRRRTQRCVE DAKIFGIQSF CKDLVEVADI LEKTTECISE ESEPEDQKLT LEKVFRGLLL LEAKLKSVFA KHGLEKLTPI GDKYDPHEHE LICHVPAGVG VQPGTVALVR QDGYKLHGRT IRLARVEVAV ESQRRL (1-225 aa encoded by B C070090)
Target Information
GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin filament-associated protein 1-like 1; AFAP1-like protein 1; GrpE protein homolog 2, mitochondrial; Mt-GrpE#2; unnamed protein product
Gene Aliases: Afap1l1; GRPEL2; Mt-GrpE#2; Mt-grpel2
UniProt ID: (Human) Q8TAA5, (Mouse) O88396
Entrez Gene ID: (Human) 134266, (Mouse) 17714, (Rat) 688777
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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