Product References
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Chinese medicine
Wang Q,Zang W,Han L,Yang L,Ye S,Ouyang J,Zhang C,Bi Y,Zhang C,Bian H
Fri Apr 08 00:00:00 EDT 2022
HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway.
Frontiers in cellular neuroscience
Xu L,Xing Q,Huang T,Zhou J,Liu T,Cui Y,Cheng T,Wang Y,Zhou X,Yang B,Yang GL,Zhang J,Zang X,Ma S,Guan F
Wed Sep 30 00:00:00 EDT 2020
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Frontiers in molecular neuroscience
Song Z,Shah SZA,Yang W,Dong H,Yang L,Zhou X,Zhao D
Wed Sep 30 00:00:00 EDT 2020
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Frontiers in physiology
Yang HF,Yu M,Jin HD,Yao JQ,Lu ZL,Yabasin IB,Yan Q,Wen QP
Wed Sep 30 00:00:00 EDT 2020
Lithium chloride inhibits cell survival, overcomes drug resistance, and triggers apoptosis in multiple myeloma via activation of the Wnt/β-catenin pathway.
American journal of translational research
Yao R,Sun X,Xie Y,Liu L,Han D,Yao Y,Li H,Li Z,Xu K
Wed Sep 30 00:00:00 EDT 2020
P21-activated kinase 7 (PAK7) interacts with and activates Wnt/β-catenin signaling pathway in breast cancer.
Journal of Cancer
Li K,Xu X,He Y,Tian Y,Pan W,Xu L,Ma Y,Gao Y,Gao J,Qi Y,Wei L,Zhang J
Wed Sep 30 00:00:00 EDT 2020
Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway.
Journal of cellular physiology
Chen C,Zhou F,Zeng L,Jiang Z,Hu Z
Mon Apr 01 00:00:00 EDT 2019
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
International journal of molecular medicine
Li W,Wang D,Sun X,Zhang Y,Wang L,Suo J
Fri Feb 01 00:00:00 EST 2019
Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway.
Mediators of inflammation
Yang Y,Sun Y,Xu J,Bao K,Luo M,Liu X,Wang Y
Tue Jan 22 00:00:00 EST 2019
High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang Y,Tang H,He G,Shi Y,Kang X,Lyu J,Zhou M,Zhu M,Zhang J,Tang K
Tue Dec 11 00:00:00 EST 2018
The neuroprotective effect of lithium chloride on cognitive impairment through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats.
European journal of pharmacology
Liu Z,Li R,Jiang C,Zhao S,Li W,Tang X
Wed Dec 05 00:00:00 EST 2018
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Phytotherapy research : PTR
Chen Y,Li Y,Wang XQ,Meng Y,Zhang Q,Zhu JY,Chen JQ,Cao WS,Wang XQ,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY
Sat Dec 01 00:00:00 EST 2018
Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway.
Oxidative medicine and cellular longevity
Zheng T,Yang X,Li W,Wang Q,Chen L,Wu D,Bian F,Xing S,Jin S
Fri Oct 26 00:00:00 EDT 2018
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Cell death & disease
Yu B,Wu K,Wang X,Zhang J,Wang L,Jiang Y,Zhu X,Chen W,Yan M
Mon Oct 22 00:00:00 EDT 2018
Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice via the PPARγ/NF-κB/NLRP3 inflammasome axis.
Acta pharmacologica Sinica
Song MT,Ruan J,Zhang RY,Deng J,Ma ZQ,Ma SP
Mon Oct 01 00:00:00 EDT 2018
The suppressive effect of soluble Klotho on fibroblastic growth factor 23 synthesis in UMR-106 osteoblast-like cells.
Cell biology international
Ma L,Gao M,Wu L,Zhao X,Mao H,Xing C
Sat Sep 01 00:00:00 EDT 2018
Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.
Cancer medicine
Li K,Ma YB,Zhang Z,Tian YH,Xu XL,He YQ,Xu L,Gao Y,Pan WT,Song WJ,He X,Wei L
Wed Aug 01 00:00:00 EDT 2018
Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention.
Toxicology letters
Wang J,Chen J,Jiang Y,Shi Y,Zhu J,Xie C,Geng S,Wu J,Zhang Q,Wang X,Meng Y,Li Y,Chen Y,Cao W,Wang X,Zhong C,Li X
Sun Jul 01 00:00:00 EDT 2018
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Journal of hematology & oncology
Wang S,Xu M,Li X,Su X,Xiao X,Keating A,Zhao RC
Thu Jun 14 00:00:00 EDT 2018
Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells.
Cancer chemotherapy and pharmacology
Zhang Q,Li XT,Chen Y,Chen JQ,Zhu JY,Meng Y,Wang XQ,Li Y,Geng SS,Xie CF,Wu JS,Zhong CY,Han HY
Fri Jun 01 00:00:00 EDT 2018
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Journal of cellular biochemistry
Li X,Meng Y,Xie C,Zhu J,Wang X,Li Y,Geng S,Wu J,Zhong C,Li M
Tue May 01 00:00:00 EDT 2018
The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation.
Journal of cellular physiology
Song N,Cao C,Tang Y,Bi L,Jiang Y,Zhou Y,Song X,Liu L,Ge W
Thu Mar 01 00:00:00 EST 2018
Silencing of lncRNA ZFAS1 inhibits malignancies by blocking Wnt/β-catenin signaling in gastric cancer cells.
Bioscience, biotechnology, and biochemistry
Xu W,He L,Li Y,Tan Y,Zhang F,Xu H
Thu Mar 01 00:00:00 EST 2018
Effects of calycosin against high-fat diet-induced nonalcoholic fatty liver disease in mice.
Journal of gastroenterology and hepatology
Duan X,Meng Q,Wang C,Liu Z,Sun H,Huo X,Sun P,Ma X,Peng J,Liu K
Thu Feb 01 00:00:00 EST 2018
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
Oncotarget
Chengye W,Yu T,Ping S,Deguang S,Keyun W,Yan W,Rixin Z,Rui L,Zhenming G,Mingliang Y,Liming W
Tue Nov 28 00:00:00 EST 2017
REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.
Experimental dermatology
Chen H,Gao X,Sun Z,Wang Q,Zuo D,Pan L,Li K,Chen J,Chen G,Hu K,Li K,Shah AS,Huang T,Muhammad Zeeshan B,Tong L,Jiao C,Liu J,Chen T,Yao L,Dang Y,Liu T,Li L
Wed Nov 01 00:00:00 EDT 2017
REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.
Experimental dermatology
Chen H,Gao X,Sun Z,Wang Q,Zuo D,Pan L,Li K,Chen J,Chen G,Hu K,Li K,Shah AS,Huang T,Muhammad Zeeshan B,Tong L,Jiao C,Liu J,Chen T,Yao L,Dang Y,Liu T,Li L
Wed Nov 01 00:00:00 EDT 2017
miR-195-5p is critical in REGγ-mediated regulation of wnt/β-catenin pathway in renal cell carcinoma.
Oncotarget
Chen S,Wang L,Yao X,Chen H,Xu C,Tong L,Shah A,Huang T,Chen G,Chen J,Liu TL,Li XT,Zheng JH,Li L
Fri Sep 08 00:00:00 EDT 2017
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Neuropharmacology
Song Z,Yang W,Zhou X,Yang L,Zhao D
Fri Sep 01 00:00:00 EDT 2017
CO-releasing molecules-2 attenuates ox-LDL-induced injury in HUVECs by ameliorating mitochondrial function and inhibiting Wnt/β-catenin pathway.
Biochemical and biophysical research communications
Sun HJ,Xu DY,Sun YX,Xue T,Zhang CX,Zhang ZX,Lin W,Li KX
Sat Aug 26 00:00:00 EDT 2017
Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang X,Tang S,Dai C,Li D,Zhang S,Deng S,Zhou Y,Xiao X
Sat Jul 01 00:00:00 EDT 2017
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
Nutrients
Chen Y,Wang XQ,Zhang Q,Zhu JY,Li Y,Xie CF,Li XT,Wu JS,Geng SS,Zhong CY,Han HY
Sat Jun 03 00:00:00 EDT 2017
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
The Journal of nutritional biochemistry
Zhu J,Wang S,Chen Y,Li X,Jiang Y,Yang X,Li Y,Wang X,Meng Y,Zhu M,Ma X,Huang C,Wu R,Xie C,Geng S,Wu J,Zhong C,Han H
Thu Jun 01 00:00:00 EDT 2017
Shp2 promotes liver cancer stem cell expansion by augmenting β-catenin signaling and predicts chemotherapeutic response of patients.
Hepatology (Baltimore, Md.)
Xiang D,Cheng Z,Liu H,Wang X,Han T,Sun W,Li X,Yang W,Chen C,Xia M,Liu N,Yin S,Jin G,Lee T,Dong L,Hu H,Wang H,Ding J
Mon May 01 00:00:00 EDT 2017
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Phytotherapy research : PTR
Zhu JY,Yang X,Chen Y,Jiang Y,Wang SJ,Li Y,Wang XQ,Meng Y,Zhu MM,Ma X,Huang C,Wu R,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY
Sat Apr 01 00:00:00 EDT 2017
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
Scientific reports
Li W,Yang X,Zheng T,Xing S,Wu Y,Bian F,Wu G,Li Y,Li J,Bai X,Wu D,Jia X,Wang L,Zhu L,Jin S
Fri Mar 17 00:00:00 EDT 2017
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Biochemical and biophysical research communications
Zhu J,Jiang Y,Yang X,Wang S,Xie C,Li X,Li Y,Chen Y,Wang X,Meng Y,Zhu M,Wu R,Huang C,Ma X,Geng S,Wu J,Zhong C
Sun Jan 01 00:00:00 EST 2017
Role of glycogen synthase kinase-3β inhibitor AZD1080 in ovarian cancer.
Drug design, development and therapy
Chen S,Sun KX,Feng MX,Sang XB,Liu BL,Zhao Y
Mon Dec 26 00:00:00 EST 2016
Polysaccharides from Pleurotus ostreatus alleviate cognitive impairment in a rat model of Alzheimer's disease.
International journal of biological macromolecules
Zhang Y,Yang X,Jin G,Yang X,Zhang Y
Tue Nov 01 00:00:00 EDT 2016
Steroid receptor coactivator-3 is a pivotal target of gambogic acid in B-cell Non-Hodgkin lymphoma and an inducer of histone H3 deacetylation.
European journal of pharmacology
Zhao Z,Zhang X,Wen L,Yi S,Hu J,Ruan J,Zhao F,Cui G,Fang J,Chen Y
Sat Oct 15 00:00:00 EDT 2016
Anti-diabetic effect of citrus pectin in diabetic rats and potential mechanism via PI3K/Akt signaling pathway.
International journal of biological macromolecules
Liu Y,Dong M,Yang Z,Pan S
Mon Aug 01 00:00:00 EDT 2016
YPEL3 suppresses epithelial-mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway.
Journal of experimental & clinical cancer research : CR
Zhang J,Wen X,Ren XY,Li YQ,Tang XR,Wang YQ,He QM,Yang XJ,Sun Y,Liu N,Ma J
Mon Jul 11 00:00:00 EDT 2016
Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
Oncology reports
Wang J,Wan X,Gao Y,Zhong M,Sha L,Liu B,Zhang W,Tian L,Ruan W,Cao S,Huang M
Fri Jul 01 00:00:00 EDT 2016
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Oncotarget
Chen S,Sun KX,Liu BL,Zong ZH,Zhao Y
Tue May 10 00:00:00 EDT 2016
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Oncotarget
Chen S,Sun KX,Liu BL,Zong ZH,Zhao Y
Tue May 10 00:00:00 EDT 2016
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Scientific reports
Dong F,Ling Q,Ye D,Zhang Z,Shu J,Chen G,Fei Y,Li C
Mon Apr 25 00:00:00 EDT 2016
Altered Wnt Signaling Pathway in Cognitive Impairment Caused by Chronic Intermittent Hypoxia: Focus on Glycogen Synthase Kinase-3β and β-catenin.
Chinese medical journal
Pan YY,Deng Y,Xie S,Wang ZH,Wang Y,Ren J,Liu HG
Tue Apr 05 00:00:00 EDT 2016
Upregulation of GSK3β Contributes to Brain Disorders in Elderly REGγ-knockout Mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Lv Y,Meng B,Dong H,Jing T,Wu N,Yang Y,Huang L,Moses RE,O'Malley BW,Mei B,Li X
Fri Apr 01 00:00:00 EDT 2016
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Oncotarget
Song Z,Zhu T,Zhou X,Barrow P,Yang W,Cui Y,Yang L,Zhao D
Tue Mar 15 00:00:00 EDT 2016
Upregulation of miR-497 induces hepatic insulin resistance in E3 rats with HFD-MetS by targeting insulin receptor.
Molecular and cellular endocrinology
Wang X,Wang M,Li H,Lan X,Liu L,Li J,Li Y,Li J,Yi J,Du X,Yan J,Han Y,Zhang F,Liu M,Lu S,Li D
Sun Nov 15 00:00:00 EST 2015
Upregulation of miR-497 induces hepatic insulin resistance in E3 rats with HFD-MetS by targeting insulin receptor.
Molecular and cellular endocrinology
Wang X,Wang M,Li H,Lan X,Liu L,Li J,Li Y,Li J,Yi J,Du X,Yan J,Han Y,Zhang F,Liu M,Lu S,Li D
Sun Nov 15 00:00:00 EST 2015
MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a.
Scientific reports
Du J,Niu X,Wang Y,Kong L,Wang R,Zhang Y,Zhao S,Nan Y
Thu Nov 05 00:00:00 EST 2015
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Scientific reports
Liu J,Huang W,Ren C,Wen Q,Liu W,Yang X,Wang L,Zhu B,Zeng L,Feng X,Zhang C,Chen H,Jia W,Zhang L,Xia X,Chen Y
Fri Jul 24 00:00:00 EDT 2015
Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.
British journal of pharmacology
Zheng T,Yang X,Wu D,Xing S,Bian F,Li W,Chi J,Bai X,Wu G,Chen X,Zhang Y,Jin S
Wed Jul 01 00:00:00 EDT 2015
RNA-binding motif protein 5 negatively regulates the activity of Wnt/β-catenin signaling in cigarette smoke-induced alveolar epithelial injury.
Oncology reports
Hao YQ,Su ZZ,Lv XJ,Li P,Gao P,Wang C,Bai Y,Zhang J
Fri May 01 00:00:00 EDT 2015
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Medical oncology (Northwood, London, England)
Zhang Y,Zhang X,Huang J,Dong Q
Fri May 01 00:00:00 EDT 2015
DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/β-catenin signaling.
Oncotarget
Liu Y,Zhou R,Yuan X,Han N,Zhou S,Xu H,Guo M,Yu S,Zhang C,Yin T,Wu K
Mon Apr 20 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
International journal of oncology
Xiao W,Jiang Y,Men Q,Yuan L,Huang Z,Liu T,Li W,Liu X
Thu Jan 01 00:00:00 EST 2015
Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells.
Molecular medicine reports
Chen XM,Xie XB,Zhao Q,Wang F,Bai Y,Yin JQ,Jiang H,Xie XL,Jia Q,Huang G
Thu Jan 01 00:00:00 EST 2015
Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia.
Metallomics : integrated biometal science
Wu Q,He J,Mei W,Zhang Z,Wu X,Sun F
Mon Dec 01 00:00:00 EST 2014
Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549.
PloS one
Chen XM,Bai Y,Zhong YJ,Xie XL,Long HW,Yang YY,Wu SG,Jia Q,Wang XH
Fri Jul 25 00:00:00 EDT 2014
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression.
Nature
Masamha CP,Xia Z,Yang J,Albrecht TR,Li M,Shyu AB,Li W,Wagner EJ
Thu Jun 19 00:00:00 EDT 2014
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
Gu GJ,Chen T,Zhou HM,Sun KX,Li J
Sat Feb 01 00:00:00 EST 2014